Malaria is a grave public health problem which represents the fifth leading cause of death from infectious diseases worldwide. Malaria is predominantly prevalent in tropical and subtropical regions, where temperature and rainfall favor the survival of malarial parasites. According to World Health Organization (WHO) estimates, 241 million malaria cases were detected globally and 627 000 malaria deaths took place worldwide in 2020. Pakistan, along with Afghanistan, Somalia, Sudan and Yemen, is reported to account for more than 95% of regional malaria burden.

In 2016, Indus Hospital & Health Network secured the Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM) grant as a private-sector principal recipient for Malaria intervention. In this, IHHN has taken the responsibility of diagnosis and management of malaria cases in intervention districts that are at high-risk. The grant was initially awarded in 2016 whereby IHHN worked with the Provincial Malaria Control Program to reduce disease burden in Balochistan and Khyber Pakhtunkhwa. Because of the success of the program and the scalable and sustainable results of the public-private partnership between IHHN and the Department of Health, the Global Fund approved funding for a further three years (January 2021-December 2023) and has continued its trust and confidence in IHHN for grant management.